Autoradiographic study of tobramycin uptake by proximal and distal tubules of normal and pyelonephritic rats.

Multiple factors may modify the pharmacokinetics of aminoglycosides and affect their nephrotoxic potential. In the present study, the influence of Escherichia coli pyelonephritis on the renal handling of [3H]tobramycin was investigated. The accumulation of [3H]tobramycin in proximal and distal tubul...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Bergeron, M G, Marois, Y, Kuehn, C, Silverblatt, F J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3314697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.9.1359
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