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Autoradiographic study of tobramycin uptake by proximal and distal tubules of normal and pyelonephritic rats.

Multiple factors may modify the pharmacokinetics of aminoglycosides and affect their nephrotoxic potential. In the present study, the influence of Escherichia coli pyelonephritis on the renal handling of [3H]tobramycin was investigated. The accumulation of [3H]tobramycin in proximal and distal tubul...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Bergeron, M G, Marois, Y, Kuehn, C, Silverblatt, F J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3314697/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.9.1359
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