Improved sensitivity in assays for binding of novel beta-lactam antibiotics to penicillin-binding proteins of Escherichia coli.

Tigemonam and temocillin, but not aztreonam, bound to penicillin-binding proteins (PBPs) 1a and 3 of Escherichia coli with apparent improved affinity when challenged with benzylpenicillin at lowered temperatures. Half times for deacylation of the tigemonam-PBP complexes were shorter than were those...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Bush, K, Smith, S A, Ohringer, S, Tanaka, S K, Bonner, D P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1987
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC174917/
https://ncbi.nlm.nih.gov/pubmed/3307621
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