Altered pharmacokinetic disposition of ciprofloxacin and vancomycin after single and multiple doses in rabbits.

The pharmacokinetic disposition of vancomycin and ciprofloxacin was assessed in rabbits before the efficacy of these compounds in experimental staphylococcal endocarditis was compared. Ciprofloxacin was given in single intravenous bolus doses of 25 and 35 mg/kg and also in a multiple-dose regimen of...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Barriere, S L, Kaatz, G W, Schaberg, D R, Fekety, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3662471/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.7.1075
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