Altered pharmacokinetic disposition of ciprofloxacin and vancomycin after single and multiple doses in rabbits.

The pharmacokinetic disposition of vancomycin and ciprofloxacin was assessed in rabbits before the efficacy of these compounds in experimental staphylococcal endocarditis was compared. Ciprofloxacin was given in single intravenous bolus doses of 25 and 35 mg/kg and also in a multiple-dose regimen of...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Barriere, S L, Kaatz, G W, Schaberg, D R, Fekety, R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1987
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3662471/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.7.1075
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