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Pharmacokinetics and tissue penetration of roxithromycin after multiple dosing.

The pharmacokinetics of the macrolide roxithromycin (RU 28965) were studied during and after administration of 150 mg every 12 h for 3 days (five doses) in six volunteers. The concentrations in serum, blister fluid, and urine were measured. Mean levels in serum taken at 1.5 h after the morning dose...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Wise, R, Kirkpatrick, B, Ashby, J, Andrews, J M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174870/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3662470/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.7.1051
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