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Pharmacokinetics and tissue penetration of roxithromycin after multiple dosing.

The pharmacokinetics of the macrolide roxithromycin (RU 28965) were studied during and after administration of 150 mg every 12 h for 3 days (five doses) in six volunteers. The concentrations in serum, blister fluid, and urine were measured. Mean levels in serum taken at 1.5 h after the morning dose...

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Bibliographic Details
Main Authors: Wise, R, Kirkpatrick, B, Ashby, J, Andrews, J M
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC174870/
https://ncbi.nlm.nih.gov/pubmed/3662470
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