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Rapid in vitro metabolic screen for antileprosy compounds.

Measurement of intracellular ATP of Mycobacterium leprae after direct in vitro exposure to antimicrobial agents was evaluated as a rapid means of identifying potentially useful therapeutic agents. Nude mouse-derived M. leprae was incubated in an axenic modified Dubos medium in the presence or absenc...

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Main Authors: Franzblau, S G, Hastings, R C
格式: Artigo
語言:Inglês
出版: 1987
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC174832/
https://ncbi.nlm.nih.gov/pubmed/3300539
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