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Rapid screening for polymorphisms in dextromethorphan and mephenytoin metabolism.

1. The phenotyping parameters for dextromethorphan and mephenytoin were assessed in 48 normal male volunteers following administration of each metabolic probe drug on separate occasions and together according to a randomized 3-way crossover design. 2. Neither the urinary S-/R-mephenytoin ratio nor t...

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Bibliographic Details
Main Authors: Guttendorf, R J, Britto, M, Blouin, R A, Foster, T S, John, W, Pittman, K A, Wedlund, P J
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380105/
https://ncbi.nlm.nih.gov/pubmed/2328190
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