Two overrepresented B cell populations in HIV-infected individuals undergo apoptosis by different mechanisms

Perturbations of B cells in HIV-infected individuals are associated with the overrepresentation of distinct B cell populations. Here we describe high extrinsic CD95 ligand (CD95L)-mediated apoptosis in CD10(−)/CD21(lo) mature/activated B cells that likely arise from HIV-induced immune activation. In...

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Bibliographic Details
Main Authors: Ho, Jason, Moir, Susan, Malaspina, Angela, Howell, Melissa L., Wang, Wei, DiPoto, Angela C., O'Shea, Marie A., Roby, Gregg A., Kwan, Richard, Mican, JoAnn M., Chun, Tae-Wook, Fauci, Anthony S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748244/
https://ncbi.nlm.nih.gov/pubmed/17158796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609515103
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