Dominance of SOX9 function over RUNX2 during skeletogenesis

Mesenchymal stem cell-derived osteochondroprogenitors express two master transcription factors, SOX9 and RUNX2, during condensation of the skeletal anlagen. They are essential for chondrogenesis and osteogenesis, respectively, and their haploinsufficiency causes human skeletal dysplasias. We show th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhou, Guang, Zheng, Qiping, Engin, Feyza, Munivez, Elda, Chen, Yuqing, Sebald, Eiman, Krakow, Deborah, Lee, Brendan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748167/
https://ncbi.nlm.nih.gov/pubmed/17142326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605170103
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg