Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis

The mechanistic/mammalian target of rapamycin complex 1 (mTORC1) regulates cellular function in various cell types. Although the role of mTORC1 in skeletogenesis has been investigated previously, here we show a critical role of mTORC1/4E-BPs/SOX9 axis in regulating skeletogenesis through its express...

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Bibliografiska uppgifter
I publikationen:Stem Cell Reports
Huvudupphovsmän: Iezaki, Takashi, Horie, Tetsuhiro, Fukasawa, Kazuya, Kitabatake, Makoto, Nakamura, Yuka, Park, Gyujin, Onishi, Yuki, Ozaki, Kakeru, Kanayama, Takashi, Hiraiwa, Manami, Kitaguchi, Yuka, Kaneda, Katsuyuki, Manabe, Takayuki, Ishigaki, Yasuhito, Ohno, Mutsuhito, Hinoi, Eiichi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117477/
https://ncbi.nlm.nih.gov/pubmed/30008325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.05.020
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