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Different patterns of inhibition of avian myeloblastosis virus reverse transcriptase activity by 3'-azido-3'-deoxythymidine 5'-triphosphate and its threo isomer.

The two isomers 3'-azido-3'-deoxythymidine 5'-triphosphate (erythro-AZT-TP) and 1-(3'-azido-2',3'-dideoxy-beta-D-xylofuranosyl)thymine 5'-triphosphate (threo-AZT-TP) were studied as inhibitors of the reverse transcriptase activity of avian myelobastosis virus. Kinetic analysis of the (rA)n X (dT)12-...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Eriksson, B, Vrang, L, Bazin, H, Chattopadhyaya, J, Oberg, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1987
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174784/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2440379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.4.600
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