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Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus.

Seven arabinosyl, 2'-deoxyribosyl, and ribosyl pyrrolo[2,3-d]pyrimidines were evaluated in vitro for activity against human cytomegalovirus and for cytotoxicity in primary and established cell lines of human origin. The parent ribosyl analogs exhibited little antiviral selectivity owing to high cyto...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Turk, S R, Shipman, C, Nassiri, R, Genzlinger, G, Krawczyk, S H, Townsend, L B, Drach, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1987
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.4.544
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