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Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus.

Seven arabinosyl, 2'-deoxyribosyl, and ribosyl pyrrolo[2,3-d]pyrimidines were evaluated in vitro for activity against human cytomegalovirus and for cytotoxicity in primary and established cell lines of human origin. The parent ribosyl analogs exhibited little antiviral selectivity owing to high cyto...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Turk, S R, Shipman, C, Nassiri, R, Genzlinger, G, Krawczyk, S H, Townsend, L B, Drach, J C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.4.544
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