Inhibition of theophylline clearance by coadministered ofloxacin without alteration of theophylline effects.

The influence of multiple doses of ofloxacin (ORF 18489) on the disposition of theophylline was studied in 15 male volunteers. Subjects were confined in the Clinical Research Unit for 13 days and given a xanthine-free diet. A single dose (3 mg/kg) of theophylline was given orally, and blood samples...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Gregoire, S L, Grasela, T H, Freer, J P, Tack, K J, Schentag, J J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3472488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.3.375
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