Inhibition of theophylline clearance by coadministered ofloxacin without alteration of theophylline effects.

The influence of multiple doses of ofloxacin (ORF 18489) on the disposition of theophylline was studied in 15 male volunteers. Subjects were confined in the Clinical Research Unit for 13 days and given a xanthine-free diet. A single dose (3 mg/kg) of theophylline was given orally, and blood samples...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gregoire, S L, Grasela, T H, Freer, J P, Tack, K J, Schentag, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3472488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.3.375
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