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Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells

Background: A common pathological feature of chronic inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) is mucus hypersecretion. MUC5AC is the predominant mucin gene expressed in healthy airways and is increased in asthmatic and COPD patients. Recent clinica...

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書誌詳細
主要な著者: Mata, M, Sarria, B, Buenestado, A, Cortijo, J, Cerda, M, Morcillo, E
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Group 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1747298/
https://ncbi.nlm.nih.gov/pubmed/15681504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2004.025692
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