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Effect of ganciclovir [9-(1,3-dihydroxy-2-propoxymethyl)guanine] on viral DNA and protein synthesis in cells infected with herpes simplex virus.

The effect of ganciclovir [9-(1,3-dihydroxy-2-propoxymethyl)guanine] on herpes simplex virus type 1 DNA and protein synthesis was studied. Ganciclovir markedly inhibited the synthesis of viral DNA and gamma proteins in a dose-dependent manner. However, the synthesis of viral beta proteins was signif...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Chun, Y S, Park, N H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3032100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.2.349
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