Inhibition of DNA gyrase by optically active ofloxacin.
Inhibition of DNA gyrase activity by optically active ofloxacins was studied and compared with the inhibition of norfloxacin and ciprofloxacin. The (-)-isomer of ofloxacin inhibited the supercoiling activity of gyrase from Micrococcus luteus more effectively than did the (+)-isomer. The 50% inhibito...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3032098/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.2.325 |
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