Chronic obstructive pulmonary disease in α(1)-antitrypsin PI MZ heterozygotes: a meta-analysis

Background: Severe α(1)-antitrypsin deficiency, usually related to homozygosity for the protease inhibitor (PI) Z allele, is a proven genetic risk factor for chronic obstructive pulmonary disease (COPD). The risk of COPD in PI MZ heterozygous individuals is controversial. Methods: A search of MEDLIN...

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Detalhes bibliográficos
Main Authors: Hersh, C, Dahl, M, Ly, N, Berkey, C, Nordestgaard, B, Silverman, E
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2004
Assuntos:
Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746834/
https://ncbi.nlm.nih.gov/pubmed/15454649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2004.022541
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