Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone.
A 400-mg dose of the trifluorinated quinolone Ro 23-6240 was administered orally to each of six healthy male volunteers, after which the concentrations of this agent in serum and cantharidin-induced inflammatory fluid were measured. Absorption was rapid, with a mean peak level in serum of 6.1 microg...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3105446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.2.161 |
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