Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone.

A 400-mg dose of the trifluorinated quinolone Ro 23-6240 was administered orally to each of six healthy male volunteers, after which the concentrations of this agent in serum and cantharidin-induced inflammatory fluid were measured. Absorption was rapid, with a mean peak level in serum of 6.1 microg...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Wise, R, Kirkpatrick, B, Ashby, J, Griggs, D J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3105446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.2.161
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