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Association of IL-10 polymorphism with severity of illness in community acquired pneumonia

Methods: Using PCR-RFLP analysis we analysed a -1082G/A single nucleotide polymorphism (SNP) of the anti-inflammatory IL-10 gene, a -308G/A SNP of the pro-inflammatory TNF-α gene and a -174G/C SNP of the IL-6 gene. Illness severity was stratified according to SIRS score, calculated by presence of up...

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Bibliografiske detaljer
Main Authors: Gallagher, P, Lowe, G, Fitzgerald, T, Bella, A, Greene, C, McElvaney, N, O'Neill, S
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746580/
https://ncbi.nlm.nih.gov/pubmed/12554901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.58.2.154
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