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Activity of (+)-cyclaradine (Sch 31172) against herpes simplex virus in vitro and in vivo.

(+)-Cyclaradine (Sch 31172) is the carbocyclic derivative of adenosine arabinoside (9-beta-D-arabinofuranosyladenine). Because it is not deaminated by deaminase in serum, as is adenosine arabinoside, (+)-cyclaradine is about 2 to 5 times more active in vitro against herpes simplex virus. (+)-Cyclara...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schwartz, J, Ostrander, M, Butkiewicz, N J, Lieberman, M, Lin, C, Lim, J, Miller, G H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC174644/
https://ncbi.nlm.nih.gov/pubmed/3032089
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