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Decreased bronchodilating effect of salbutamol in relieving methacholine induced moderate to severe bronchoconstriction during high dose treatment with long acting β(2) agonists
BACKGROUND—In vitro the long acting β(2) agonist salmeterol can, in contrast to formoterol, behave as a partial agonist and become a partial antagonist to other β(2) agonists. To study this in vivo, the bronchodilating effect of salbutamol was measured during methacholine induced moderate to severe...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1746085/ https://ncbi.nlm.nih.gov/pubmed/11413351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.56.7.529 |
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