Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment

BACKGROUND—Nitric oxide (NO) and prostanoids are mediators of vascular and bronchial tone that are postulated to be involved in asthma. Increased levels of both are found in asthmatic subjects and are synthesised by enzymes that have cytokine inducible forms: inducible NO synthase (iNOS) and cyclo-o...

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Détails bibliographiques
Auteurs principaux: Redington, A, Meng, Q, Springall, D, Evans, T, Creminon, C, Maclouf, J, Holgate, S, Howarth, P, Polak, J
Format: Artigo
Langue:Inglês
Publié: BMJ Group 2001
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746058/
https://ncbi.nlm.nih.gov/pubmed/11312402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.56.5.351
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