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Association of IL-1β and IL-1 receptor antagonist haplotypes with rate of decline in lung function in smokers

BACKGROUND—There is increasing evidence that the cytokine network is central to the immunopathology of inflammatory airway diseases. The interleukin 1 (IL-1) receptor antagonist (IL-1RN) is a naturally occurring anti-inflammatory agent that binds to the IL-1 receptor but does not possess agonist act...

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Detalhes bibliográficos
Main Authors: Joos, L, McIntyre, L, Ruan, J, Connett, J, Anthonisen, N, Weir, T, Pare, P, Sandford, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745962/
https://ncbi.nlm.nih.gov/pubmed/11641511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.56.11.863
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