Evaluation of recombinant transferrin-binding protein B variants from Neisseria meningitidis for their ability to induce cross-reactive and bactericidal antibodies against a genetically diverse collection of serogroup B strains.

Transferrin-binding protein B (TbpB) is a surface-exposed protein, variable among strains of Neisseria meningitidis, that has been considered as a vaccine candidate. To define a TbpB molecule that would give rise to broadly cross-reactive antibodies with TbpB of many strains, specific antisera were...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Rokbi, B, Mignon, M, Maitre-Wilmotte, G, Lissolo, L, Danve, B, Caugant, D A, Quentin-Millet, M J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8975892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.1.55-63.1997
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