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Evaluation of recombinant transferrin-binding protein B variants from Neisseria meningitidis for their ability to induce cross-reactive and bactericidal antibodies against a genetically diverse collection of serogroup B strains.

Transferrin-binding protein B (TbpB) is a surface-exposed protein, variable among strains of Neisseria meningitidis, that has been considered as a vaccine candidate. To define a TbpB molecule that would give rise to broadly cross-reactive antibodies with TbpB of many strains, specific antisera were...

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Bibliografische gegevens
Hoofdauteurs: Rokbi, B, Mignon, M, Maitre-Wilmotte, G, Lissolo, L, Danve, B, Caugant, D A, Quentin-Millet, M J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC174556/
https://ncbi.nlm.nih.gov/pubmed/8975892
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