Construction of a flagellum-negative mutant of Proteus mirabilis: effect on internalization by human renal epithelial cells and virulence in a mouse model of ascending urinary tract infection.

To examine the role of flagella in pathogenesis of urinary tract infection caused by Proteus mirabilis, we constructed a nonmotile, nonswarming flagellum mutant of strain WPM111 (an hpmA hemolysin mutant of strain BA6163, chosen because of its lack of in vitro cytotoxicity in renal epithelial cell i...

詳細記述

保存先:
書誌詳細
主要な著者: Mobley, H L, Belas, R, Lockatell, V, Chippendale, G, Trifillis, A L, Johnson, D E, Warren, J W
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC174527/
https://ncbi.nlm.nih.gov/pubmed/8945585
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