Attenuated virulence of uridine-uracil auxotrophs of Aspergillus fumigatus.
Aspergillus fumigatus mutants that are deficient in the de novo UMP biosynthesis pathway because of a mutation in the pyrG gene encoding orotidine-5'-phosphate decarboxylase (and therefore auxotrophic for uridine or uracil) were evaluated in a murine model of invasive aspergillosis. These mutants we...
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| Опубликовано в:: | Infect Immun |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1996
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8926121/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.10.4401-4405.1996 |
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