Tumor necrosis factor primes neutrophils to kill Staphylococcus aureus by an oxygen-dependent mechanism and Plasmodium falciparum by an oxygen-independent mechanism.

The cytokine tumor necrosis factor (TNF) plays the important role of priming neutrophils for increased antimicrobial activity. We now demonstrate that human neutrophils which lack the ability to generate oxygen radicals, from patients with chronic granulomatous disease, show TNF-induced enhancement...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Kowanko, I C, Ferrante, A, Clemente, G, Kumaratilake, L M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8757889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.8.3435-3437.1996
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