pH-dependent penicillin tolerance may protect intraleukocytic Staphylococcus aureus from killing by cloxacillin.
Exposure of Staphylococcus aureus to cloxacillin at neutral pH rendered the bacteria more susceptible to subsequent lysis by lysostaphin. This sensitization effect also occurred at lower pH levels which were nonpermissive for the bactericidal action of cloxacillin, but the effect disappeared at pH 5...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7081980/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.4.618 |
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