Interleukin-10 protects neonatal mice from lethal group B streptococcal infection.

We investigated the role of interleukin-10 (IL-10) in a neonatal mouse model of lethal group B streptococci (GBS) sepsis. Plasma IL-10 levels significantly increased at 24 and 48 h after GBS inoculation. Neutralization of IL-10 with specific antibodies had no effect on lethality. Administration of r...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Cusumano, V, Genovese, F, Mancuso, G, Carbone, M, Fera, M T, Teti, G
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174154/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.7.2850-2852.1996
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