Bacterial persistence and immunity in goats vaccinated with a purE deletion mutant or the parental 16M strain of Brucella melitensis.

To evaluate host responses, young goats were inoculated subcutaneously with a genetic deletion mutant (deltapurE201) of Brucella melitensis (n = 6), its virulent parental strain 16M (n = 6), or saline (n = 6). No clinical evidence of brucellosis was seen in any goat. Serum antibody titers peaked at...

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Publicado en:	Infect Immun
Autores principales:	Cheville, N F, Olsen, S C, Jensen, A E, Stevens, M G, Florance, A M, Houng, H S, Drazek, E S, Warren, R L, Hadfield, T L, Hoover, D L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698463/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.7.2431-2439.1996
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