Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease?

Background: It has been proposed that, independent of the ε4 allele, APOE promoter polymorphisms (–491 A/T and –219 G/T) may be risks factor for Alzheimer's disease by modulating APOE expression. Objective: To measure the level of APOE expression in Alzheimer's disease. Methods: Brains wer...

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Detalhes bibliográficos
Main Authors: Lambert, J, Mann, D, Richard, F, Tian, J, Shi, J, Thaker, U, Merrot, S, Harris, J, Frigard, B, Iwatsubo, T, Lendon, C, Amouyel, P
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2005
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Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1739723/
https://ncbi.nlm.nih.gov/pubmed/15965197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2004.048983
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