Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses.

Mucosal immunoglobulin A (IgA) responses are often associated with Th2-type cells and derived cytokines, and interleukin-4 (IL-4) knockout (IL-4-/-) mice with impaired Th2 cells respond poorly to oral antigens. However, we have noted that IL-4-/- mice have normal mucosal IgA levels, which led us to...

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書誌詳細
出版年:	Infect Immun
主要な著者:	Okahashi, N, Yamamoto, M, Vancott, J L, Chatfield, S N, Roberts, M, Bluethmann, H, Hiroi, T, Kiyono, H, McGhee, J R
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1996
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8613355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.5.1516-1525.1996
タグ:	タグ追加タグなし, このレコードへの初めてのタグを付けませんか!

Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses.

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