Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses.

Mucosal immunoglobulin A (IgA) responses are often associated with Th2-type cells and derived cytokines, and interleukin-4 (IL-4) knockout (IL-4-/-) mice with impaired Th2 cells respond poorly to oral antigens. However, we have noted that IL-4-/- mice have normal mucosal IgA levels, which led us to...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Okahashi, N, Yamamoto, M, Vancott, J L, Chatfield, S N, Roberts, M, Bluethmann, H, Hiroi, T, Kiyono, H, McGhee, J R
פורמט: Artigo
שפה:Inglês
יצא לאור: 1996
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC173956/
https://ncbi.nlm.nih.gov/pubmed/8613355
תגים: הוספת תג
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