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A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients

Objectives: The cytokine interleukin (IL)-1 mediates ischaemic brain damage in rodents. The endogenous, highly selective, IL-1 receptor antagonist (IL-1ra) protects against ischaemic cerebral injury in a range of experimental settings, and IL-1ra causes a marked reduction of cell death when administ...

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Detalhes bibliográficos
Main Authors: Emsley, H, Smith, C, Georgiou, R, Vail, A, Hopkins, S, Rothwell, N, Tyrrell, P, t for
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1739363/
https://ncbi.nlm.nih.gov/pubmed/16170078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2004.054882
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