The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial

BACKGROUND: Interleukin-1 (IL-1) is a key mediator of ischaemic brain injury induced by stroke and subarachnoid haemorrhage (SAH). IL-1 receptor antagonist (IL-1Ra) limits brain injury in experimental stroke and reduces plasma inflammatory mediators associated with poor outcome in ischaemic stroke p...

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Detalhes bibliográficos
Main Authors: Singh, Navneet, Hopkins, Stephen J, Hulme, Sharon, Galea, James P, Hoadley, Margaret, Vail, Andy, Hutchinson, Peter J, Grainger, Samantha, Rothwell, Nancy J, King, Andrew T, Tyrrell, Pippa J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892121/
https://ncbi.nlm.nih.gov/pubmed/24383930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-1
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