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Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: variation by age and sex

Background: The risk effect of APOE ε4 allele for Alzheimer's disease is acknowledged, whereas the putative protective effect of ε2 allele remains in debate. Objectives: To investigate whether those inconsistent findings may be attributable to differences in age and sex composition of the study...

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Библиографические подробности
Главные авторы: Qiu, C, Kivipelto, M, Aguero-Torres, H, Winblad, B, Fratiglioni, L
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Group 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1739059/
https://ncbi.nlm.nih.gov/pubmed/15145993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2003.021493
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