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Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression.

To characterize the mechanism by which interleukin 10 (IL-10) inhibits Th1 responses to intracellular pathogens, we evaluated the interaction between IL-10 and Mycobacterium tuberculosis-induced gamma interferon (IFN-gamma) production by peripheral blood mononuclear cells from persons across the spe...

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Detalhes bibliográficos
Main Authors: Gong, J H, Zhang, M, Modlin, R L, Linsley, P S, Iyer, D, Lin, Y, Barnes, P F
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC173856/
https://ncbi.nlm.nih.gov/pubmed/8641800
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