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Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression.

To characterize the mechanism by which interleukin 10 (IL-10) inhibits Th1 responses to intracellular pathogens, we evaluated the interaction between IL-10 and Mycobacterium tuberculosis-induced gamma interferon (IFN-gamma) production by peripheral blood mononuclear cells from persons across the spe...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Gong, J H, Zhang, M, Modlin, R L, Linsley, P S, Iyer, D, Lin, Y, Barnes, P F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173856/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8641800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.3.913-918.1996
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