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Attenuated nuclear shrinkage in neurones with nuclear inclusions of SCA1 brains

Background: Spinocerebellar ataxia type 1 (SCA1) is one of the autosomal dominant neurodegenerative disorders commonly linked to pathological expansion of the CAG repeat of the relevant gene. Nuclear inclusions and neurodegeneration are both triggered by this pathological expansion of the CAG/polygl...

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Detalhes bibliográficos
Main Authors: Nagaoka, U, Uchihara, T, Iwabuchi, K, Konno, H, Tobita, M, Funata, N, Yagishita, S, Kato, T
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1738416/
https://ncbi.nlm.nih.gov/pubmed/12700301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.74.5.597
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