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Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease

Objective: To test the hypothesis that polymorphic variation in insulin signalling genes may underlie the shared risk of dysfunctional insulin signalling and late onset Alzheimer's disease (AD). The p85α subunit of phosphatidyl inositol 3 kinase (PIK3R1) and the regulatory subunit 3 of protein...

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Detalhes bibliográficos
Main Authors: Liolitsa, D, Powell, J, Lovestone, S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1738023/
https://ncbi.nlm.nih.gov/pubmed/12185156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.73.3.261
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