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C5a peptidase alters clearance and trafficking of group A streptococci by infected mice.

Group A streptococcal C5a peptidase (SCPA) specifically cleaves the human serum chemotaxin C5a at the polymorphonuclear leukocyte (PMNL) binding site. This study tested the proposal that SCPA contributes to virulence by retarding the influx of inflammatory cells and clearance of streptococci during...

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Main Authors: Ji, Y, McLandsborough, L, Kondagunta, A, Cleary, P P
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC173793/
https://ncbi.nlm.nih.gov/pubmed/8550199
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