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Orally administered microencapsulated Bordetella pertussis fimbriae protect mice from B. pertussis respiratory infection.

Fimbriae from Bordetella pertussis have been encapsulated in poly(lactide-co-glycolide) microparticles of a size appropriate for uptake by the immune inductive tissues of the gastrointestinal tract. Mice were immunized by oral gavage with a single dose of 10 micrograms of microencapsulated fimbriae....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Jones, D H, McBride, B W, Thornton, C, O'Hagan, D T, Robinson, A, Farrar, G H
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8550197/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.2.489-494.1996
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