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Functional analysis of pneumolysin by use of monoclonal antibodies.

We have produced a panel of monoclonal antibodies to pneumolysin, the membrane-damaging toxin from Streptococcus pneumoniae. We have used these antibodies to identify three regions of the toxin sequence that are involved in the lytic mechanism of this toxin. Two of these sites probably form the cell...

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Detalhes bibliográficos
Main Authors: de los Toyos, J R, Méndez, F J, Aparicio, J F, Vázquez, F, Del Mar García Suárez, M, Fleites, A, Hardisson, C, Morgan, P J, Andrew, P W, Mitchell, T J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC173789/
https://ncbi.nlm.nih.gov/pubmed/8550195
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