Reconsideration of biallelic inactivation of the VHL tumour suppressor gene in hemangioblastomas of the central nervous system

OBJECTIVES—Cerebellar haemangioblastoma occurs sporadically or as a component tumour of autosomal dominant von Hippel-Lindau disease. Biallelic inactivation of the VHL tumour suppressor gene, which is located on chromosome 3p, has been shown to be involved in the pathogenesis of both tumour entities...

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Bibliografiske detaljer
Main Authors: Glasker, S, Bender, B, Apel, T, van Velthoven, V, Mulligan, L, Zentner, J, Neumann, H
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2001
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1737358/
https://ncbi.nlm.nih.gov/pubmed/11309459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.70.5.644
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